TR

  • Personnel Profile | Academic

Cover Image
profile_image

Asst. Prof. Dr. Mohammed T. N. QAOUD

Faculty of Pharmacy/Pharmacy
Download Contact
E-mail:
mqaoud@ciu.edu.tr
Phone No:
+90 392 671 11 11
Extension:
2658
Office:
244
Al azar Uni.

Eczacılık (Undergraduate , 2011)

Jordan Uni. of Science & Technology

Farmasötik Teknoloji (Master , 2017)

Gazi Üni.

Farmasötik Kimya (PhD , 2023)

    Articles published in peer reviewed international journals (SCI,SSCI,Arts and Humanities)
  • Daşman, M., Qaoud, M. T., & Abudayyak, M. (2026). Deciphering the mechanisms of Cupferron reproductive toxicity: insights from in vitro assays, network toxicology, and molecular docking. Toxicological Sciences, 209(3). https://doi.org/10.1093/toxsci/kfag014 - 2026
  • Küçükkahraman, G., Zengin, Ö. S., Qaoud, M. T., Arici, M., & Özhan, G. (2026). Polypharmacological neurotoxic effects of methylisothiazolinone revealed by integrated in vitro and network-based chemoinformatics approaches. The Journal of Toxicological Sciences, 51(9), 471-487. DOI: 10.2131/jts.51.471 - 2026
  • Doosti, M. M., & Qaoud, M. T. (2027). Molecular engineering of insulin analogues for oral bioavailability: A systematic review of structural modifications and formulation stability. Journal of Drug Delivery Science and Technology, 127, 108941. https://doi.org/10.1016/j.jddst.2026.108941 - 2026
  • Çapan, İ., Yasa, Ç., Demir, Y., Güzelcan, M., Qaoud, M. T., Sert, Y., Koca, İ., & Gülçin, İ. (2026). Probing novel azole–sulfonamide urea/thiourea conjugates as multitarget inhibitors of AChE and hCAs (I and II): synthesis, in vitro, and in silico studies. Medicinal Chemistry Research. https://doi.o - 2026
  • Novel carbazole-thiadiazole derivatives as α-amylase and α-glucosidase inhibitors: Design, biological evaluation, and computational insights. Irfan Çapan, Mohammed Hawash, Mohammed T. Qaoud, Nidal Jaradat. Bioorganic Chemistry. 03-02-2025. https://doi.org/10.1016/j.bioorg.2025.108243 - 2025
  • In vitro investigation of the toxicological mechanisms of Fingolimod (S)-phosphate in HEPG2 cells. Toxicology Research 14, no. 3 (2025): tfaf064. Bilgehan, Ayşenur, Zehra Şeker, Mohammed T. Qaoud, and Gül Özhan. https://doi.org/10.1093/toxres/tfaf064 - 2025
  • Reproductive toxicity potential of Fluazifop-butyl: In vitro, network toxicology, and molecular docking insights. Aysenur Bilgehan, Merve Arici, Mohammed T Qaoud, and Gül Ozhan. Pesticide Biochemistry and Physiology. DOI: https://doi.org/10.1016/j.pestbp.2025.106514. Accepted date: 13 June 2025 - 2025
  • Thiazole-carboxamide derivatives as potent antioxidant agents with drug-like properties: In vitro, molecular docking, and DFT studies. PloS one. 2025 Sep 19;20(9):e0331000. Mohammed Hawash* , Mohammed T. Qaoud* et al. https://doi.org/10.1371/journal.pone.0331000. - 2025
  • Steroidal Arylidene Hybrids with Phenolic Moieties: Integrated In Silico, DFT, and Electrochemical Evaluation for Therapeutic Targeting." Journal of Molecular Structure (2025): 144297. https://doi.org/10.1016/j.molstruc.2025.144297. Mohammed T. Qaoud, Irfan Çapan, Sinan Saydam, Süleyman Servi - 2025
  • Hawash, M., Shweiki, N., Qaoud, M. T. et. al. (2025). Trifluoromethyl–pyrazole–carboxamides as COX inhibitors: synthesis, microed structural analysis, computational profiling, and biological evaluation. BMC chemistry, 19(1), 288.10.1186/s13065-025-01659-z - 2025
  • Arici, Merve, Ayşenur Bilgehan, Mohammed T. Qaoud, and Gül Özhan. "Investigating Penthiopyrad’s Potential Toxicity on Male Reproductive Health via In Vitro Models and Computational Network Toxicology and Docking Studies." Chemico-Biological Interactions (2025): 111840. DOI: 10.1016/j.cbi.2025.111840 - 2025
  • Synthesis of novel carbazole hydrazine-carbothioamide scaffold as potent antioxidant, anticancer and antimicrobial agents. İrfan Çapan, Mohammed Hawash, Mohammed T. Qaoud et al BMC chemistry. 2024 May 21;18(1):102. https://doi.org/10.1186/s13065-024-01207-1 - 2024
  • Effects of lesinurad on HEK-293 human kidney cells: In vitro and molecular docking evaluation. Tugce BORAN, Mahmoud ABUDAYYAK, Mohammed T. QAOUD Journal of Research in Pharmacy. 2024;28(3). http://dx.doi.org/10.29228/jrp.733 - 2024
  • Biological, phytochemical and molecular docking characteristics of Laurus nobilis L. fresh leaves essential oil from Palestine. Jaradat, Hawash, Qaoud MT et al BMC Complementary Medicine and Therapies. 2024;24. 10.1186/s12906-024-04528-9 - 2024
  • Tripeptide linked dispiro cyclotriphosphazene conjugates: Synthesis, molecular docking analysis of compounds binding within cancer cell line receptors and in vitro cytotoxic and genotoxic activities. Çalışkan, Capan, Qaoud MT et al Bioorganic Chemistry. https://doi.org/10.1016/j.bioorg.2024.107621 - 2024
  • Integrative bioinformatic and experimental analysis of benzoylbenzodioxol derivatives: hypoglycemic potential in diabetic mice. Hawash, Jaradat, Abualhasan, Jadallah, Fashafsheh, Zaid, Qamhia, Qneibi, Qaoud MT et al 3 Biotech. 2024 Oct;14(10):1-4. https://doi.org/10.1007/s13205-024-04103-6 - 2024
  • Development of tripeptide-cyclotriphosphazene derivatives: In vitro cytotoxicity, genotoxicity studies and molecular docking analysis within ovarian and prostate cancer cell line receptors. Kaplan, Çalışkan, Çapan, Tekin, Hassan, Qaoud MT, et al Polyhedron. 2024. https://doi.org/10.1016/j.poly.2024 - 2024
  • Phosphazene Tripeptide Conjugates: Design, Synthesis, In Vitro Cytotoxicity and Genotoxicity, Molecular Interactions in Binding Pockets on Human Breast and Colon Cancer Cell Lines. Eray,Furkan, İrfan, Suat, Reda, Mohammed T. Qaoud, ChemMedChem. 2024. https://doi.org/10.1002/cmdc.202400570 - 2024
  • Next-Generation Carbazole-Linked 1, 2, 4-Triazole-Thione Derivatives: Strategic Design, Synthesis, Molecular Docking, and Evaluation of Antidiabetic Potential. IrfanCapan,*MohammedHawash,MohammedT.Qaoud, and Nidal Jaradat. ACS Omega. 2024. https://doi.org/10.1021/acsomega.4c07896 - 2024
  • Molecular docking studies and biological evaluation of isoxazole-carboxamide derivatives as COX inhibitors and antimicrobial agents. Hawash M, Jaradat N, Abualhasan M, Qaoud MT et al 3 Biotech. 2022 Dec;12(12):342. https://doi.org/10.1007/s13205-022-03408-8 - 2023
  • Anticancer activity of thiophene carboxamide derivatives as CA-4 biomimetics: Synthesis, biological potency, 3D spheroid model, and molecular dynamics simulation. Hawash M, Qaoud MT et al Biomimetics. 2022 Dec 17;7(4):247. https://doi.org/10.3390/biomimetics7040247 - 2023
  • New thiazole carboxamide derivatives as COX inhibitors: design, synthesis, anticancer screening, in silico molecular docking, and ADME profile studies. Hawash M, Jaradat N, Sabobeh R, Abualhasan M, Qaoud MT. ACS omega. 2023 Aug 6;8(32):29512-26. https://doi.org/10.1021/acsomega.3c03256 - 2023
  • Design, synthesis, molecular docking studies and biological evaluation of thiazole carboxamide derivatives as COX inhibitors. Hawash,Jaradat,Abualhasan, Kadır Şüküroğlu, Mohammed T. Qaoud et al BMC chemistry. 2023 Mar 6;17(1):11. https://doi.org/10.1186/s13065-023-00924-3 - 2023
  • Antidiabetic, antioxidant, and anti-obesity effects of phenylthio-ethyl benzoate derivatives, and molecular docking study regarding α-amylase enzyme. Jaradat N, Khasati A, Hawi M, Hawash M, Shekfeh S, Qneibi M, Eid AM, Arar M, Qaoud MT. Scientific Reports. 2022, https://doi.org/10.1038/s41598-022 - 2022
  • Peroxisome proliferator-activated receptors as superior targets for treating diabetic disease, design strategies-review article. T QAOUD M, Almasri I, Önkol T. Turkish Journal of Pharmaceutical Sciences. 2022 Jun 27;19(3):353. https://doi.org/10.4274%2Ftjps.galenos.2021.70105 - 2022
  • The ultrashort peptide OW: a new antibiotic adjuvant. Al Tall Y, Abualhaijaa A, Qaoud MT, Alsaggar M, Masadeh M, Alzoubi KH. Current pharmaceutical biotechnology. 2019, https://doi.org/10.2174/1389201020666190618111252 - 2019
  • Antimicrobial and antibiofilm activity of UP-5, an ultrashort antimicrobial peptide designed using only arginine and biphenylalanine. Almaaytah A, Qaoud MT et al Pharmaceuticals. 2018 Jan 2;11(1):3. https://doi.org/10.3390/ph11010003 - 2018
  • Hybridization and antibiotic synergism as a tool for reducing the cytotoxicity of antimicrobial peptides. Almaaytah A, Qaoud MT, Abualhaijaa A, Al-Balas Q, Alzoubi KH. Infection and drug resistance. 2018, https://doi.org/10.2147/IDR.S166236 - 2018
    • Articles published in other peer reviewed international journals
  • Homology Modeling of Human Indoleamine-Pyrrole 2, 3-Dioxygenase-2 (hIDO2) and Virtual Screening Approaches to Identify Novel, Potent, and Selective HIDO2 Inhibitors. Mohammed Qaoud, Murat Şüküroğlu Palestinian Medical and Pharmaceutical Journal. 2023;8(3):11. https://doi.org/10.59049/2790-0231.125 - 2023
  • Technical insight into biodegradable polymers used in implants. Masadeh R, Qaoud M. et al Jordan Journal of Pharmaceutical Sciences. 2018 Sep 19;11(3). https://archives.ju.edu.jo/index.php/jjps/article/view/102520 - 2018
  • Design of New COX-I/II Enzyme Inhibitor Candidates and Evaluation of Their Activities - 2025
  • I am an experienced researcher with a robust track record in the fields of drug design and ADMET development, homology modeling, and molecular docking studies. My expertise also extends to organic chemistry, where I have conducted extensive research in NMR and LCMS spectrometry analysis. Additionally, my work encompasses the exciting realm of nanotechnology, where I have been involved in innovative projects. Furthermore, I have a keen interest in antimicrobial peptide design, synthesis, analysis, and evaluation, a crucial area in today's world of evolving pathogens. My research also delves into the intricacies of toxicity assessment and MTT antiproliferative studies, contributing valuable insights to drug development and safety. With a deep passion for interdisciplinary science, my work strives to bridge the gap between molecular insights and practical applications in the pursuit of novel therapeutic solutions.
    Master Thesis Supervised

  • The design of highly potent ultrashort conjugated antimicrobial peptides against planktonic and biofilm forming methicillin-resistant Staphylococcus aureus - 2017

    • Doctorate Thesis Supervised

  • Synthesis and Investigation the Biological Activity of New İndolamine-Pyrrole 2,3-Dioxygenase (hIDO) Inhibitors Derived from Procurer Compounds Based on Chemical Modification and Virtual Screening Method. - 2023